[AX5]

Code

If RadioButton1.Enabled Then ' Firefox
    Process.Start("E:\Program Files (x86)\Mozilla Firefox\firefox.exe", TextBox1.Text)
  ElseIf RadioButton2.Enabled Then
    Process.Start("C:\Program Files (x86)\Google\Chrome\Application\chrome.exe", TextBox1.Text)
  End If

Works on both :) have fun

[AX5]

Don't hold it to me, but i think he may mean within his VB.Net Application, and not an external program.

That also presumes that the user has a Programs File on C:\ and E:\, and firefox is installed in the default directory...of E:\....

Hmm sure, I have 2 HDD and one of the browsers was installed on the E drive. ^^

[AX5]

I need it to be opened inside my application not an external application. Please look at the diagram.

yeah my bad sir. I did and i have no idea :P

[iiRex]

I think this might be what you're looking for:
http://www.youtube.com/watch?v=2hmOoCOiDYM

EDIT: Btw, you might need to change some of the code, that however should be fairly simple.