[Internet Explorer.]

Not sure if infected, could someone check my PC?

[Niko]

I've seen many cases of this, The 2 most common things are, Some people's skypes will cause a clicking Noise, as well as a loading sign on their mouse when a new ad is on skype. Another cause could be a rat accessing your files (Most you don't hear though).

To Rule Out A Malware Cause,

Please download Farbar Recovery Scan Tool. Make sure to get the one compatible with your system. http://www.bleepingcomputer.com/download...scan-tool/

Save it to your desktop.

Right click "Run as administrator"

Click Scan

It will output 2 logs "FRST.txt" and "Addition.txt" to your desktop. Post them on pastebin and reply with the links. Someone more advanced with malware removal will assist you in the removal process.

[Internet Explorer.]

Nevermind, it was just Skype.
Thanks LegitBytes.